Lactobacillus gasseri

Lactobacillus gasseri
Scientific classification Edit this classification
Domain: Bacteria
Kingdom: Bacillati
Phylum: Bacillota
Class: Bacilli
Order: Lactobacillales
Family: Lactobacillaceae
Genus: Lactobacillus
Species:
L. gasseri
Binomial name
Lactobacillus gasseri
Lauer and Kandler 1980

Lactobacillus gasseri is a species in the genus Lactobacillus identified in 1980 by François Gasser and his associates.[1][2]

L. gasseri is a normal inhabitant of the intestines of men and women and lower reproductive tract in healthy women.[3] It is one of the four main species of Lactobacillus considered to be the major part of the vaginal microbiota, along with Lactobacillus crispatus, Lactobacillus jensenii, and Lactobacillus iners.[4]

Lactobacillus gasseri produces gassericin A, a bacteriocin.[5] It also produces Lactocillin.[6]

Its 1.89 Mbp genome was sequenced in 2008.[7]

Its strain Lg-36 eliminates C. difficile infection after taking antibiotics.[8]

Relation to humans

Visceral fat

Multiple studies have reported that L. gasseri (specifically strains BNR17 and SBT2055) may reduce visceral fat, body weight, and waist circumference by decreasing fat absorption. Daily consumption over 12 weeks can lead to significant reductions in abdominal fat areas in human adults.[9][10]

References

  1. ^ Johnson, J. L.; Phelps, C. F.; Cummins, C. S.; London, J.; Gasser, F. (1980). "Taxonomy of the Lactobacillus acidophilus Group". International Journal of Systematic Bacteriology. 30 (1): 53–68. doi:10.1099/00207713-30-1-53. ISSN 0020-7713.
  2. ^ Lauer, Eckhard; Kandler, Otto (February 1980). "Lactobacillus gasseri sp. nov., a new species of the subgenus Thermobacterium". Zentralblatt für Bakteriologie: I. Abt. Originale C: Allgemeine, angewandte und ökologische Mikrobiologie. 1 (1): 75–78. doi:10.1016/S0172-5564(80)80019-4.
  3. ^ Nardis, C.; Mastromarino, P.; Mosca, L. (September 2013). "Vaginal microbiota and viral sexually transmitted diseases". Annali di Igiene. 25 (5): 443–56. doi:10.7416/ai.2013.1946. PMID 24048183.
  4. ^ Ravel, J; Gajer, P; Abdo, Z; Schneider, GM; Koenig, SS; McCulle, SL; Karlebach, S; Gorle, R; Russell, J; Tacket, CO; Brotman, RM; Davis, CC; Ault, K; Peralta, L; Forney, LJ (15 March 2011). "Vaginal microbiome of reproductive-age women". Proceedings of the National Academy of Sciences of the United States of America. 108 Suppl 1 (Suppl 1): 4680–7. doi:10.1073/pnas.1002611107. PMC 3063603. PMID 20534435.
  5. ^ [1] Archived 2017-02-19 at the Wayback MachinePandey N, Malik RK, Kaushik JK, Singroha G (2013). "Gassericin A: a circular bacteriocin produced by lactic acid bacteria Lactobacillus gasseri". World Journal of Microbiology & Biotechnology. 29 (11): 1977–87. doi:10.1007/s11274-013-1368-3. PMID 23712477. S2CID 30931536. Retrieved 2017-02-18 – via ResearchGate.net.
  6. ^ Check Hayden, Erika (11 September 2014). "Vaginal microbe yields novel antibiotic". Nature. doi:10.1038/nature.2014.15900. S2CID 211729548.
  7. ^ Azcarate-Peril, M. A.; Altermann, E.; Goh, Y. J.; Tallon, R.; Sanozky-Dawes, R. B.; Pfeiler, E. A.; O'Flaherty, S.; Buck, B. L.; Dobson, A.; Duong, T.; Miller, M. J.; Barrangou, R.; Klaenhammer, T. R. (2008). "Analysis of the Genome Sequence of Lactobacillus gasseri ATCC 33323 Reveals the Molecular Basis of an Autochthonous Intestinal Organism". Applied and Environmental Microbiology. 74 (15): 4610–4625. Bibcode:2008ApEnM..74.4610A. doi:10.1128/AEM.00054-08. ISSN 0099-2240. PMC 2519322. PMID 18539810.
  8. ^ Foley, Matthew H.; McMillan, Arthur S.; O'Flaherty, Sarah; Thanissery, Rajani; Vanhoy, Molly E.; Fuller, Mary Gracen; Barrangou, Rodolphe; Theriot, Casey M. (2025-07-21). "Differential modulation of post-antibiotic colonization resistance to Clostridioides difficile by two probiotic Lactobacillus strains". mBio. 0 (0): e01468–25. doi:10.1128/mbio.01468-25.
  9. ^ Kim, Joohee; Yun, Jae Moon; Kim, Mi Kyung; Kwon, Oran; Cho, Belong (May 2018). "Lactobacillus gasseri BNR17 Supplementation Reduces the Visceral Fat Accumulation and Waist Circumference in Obese Adults: A Randomized, Double-Blind, Placebo-Controlled Trial". Journal of Medicinal Food. 21 (5): 454–461. doi:10.1089/jmf.2017.3937. ISSN 1557-7600. PMID 29688793.
  10. ^ Kadooka, Yukio; Sato, Masao; Ogawa, Akihiro; Miyoshi, Masaya; Uenishi, Hiroshi; Ogawa, Hitomi; Ikuyama, Ken; Kagoshima, Masatoyo; Tsuchida, Takashi (2013-11-14). "Effect of Lactobacillus gasseri SBT2055 in fermented milk on abdominal adiposity in adults in a randomised controlled trial". The British Journal of Nutrition. 110 (9): 1696–1703. doi:10.1017/S0007114513001037. ISSN 1475-2662. PMID 23614897.

Further reading


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