CACNG1

CACNG1
标识符
代号	CACNG1
扩展标识	OMIM：114209；MGI：1206582；HomoloGene：582；GeneCards：CACNG1；OMA：CACNG1 - orthologs
基因位置（人类）
染色体	17號染色體
终止	67,056,797 bp
基因位置（小鼠）
染色体	小鼠11号染色体
终止	107,607,348 bp
RNA表达模式
	Top expressed in
	muscle of thigh; ; skeletal muscle tissue; ; Skeletal muscle tissue of rectus abdominis; ; Skeletal muscle tissue of biceps brachii;
	Top expressed in
	muscle of thigh; ; medial head of gastrocnemius muscle;
	查阅更多表达数据
	查阅更多表达数据
基因本體
分子功能	voltage-gated calcium channel activity; 血浆蛋白结合; voltage-gated ion channel activity; calcium channel activity; calcium channel regulator activity;
細胞組分	電壓依賴性鈣通道; integral component of membrane; 细胞膜; 膜; integral component of plasma membrane; 横小管; 肌膜; L-type voltage-gated calcium channel complex;
生物學過程	regulation of ion transmembrane transport; 肌肉收缩; ion transport; calcium ion transmembrane transport; sarcoplasmic reticulum calcium ion transport; calcium ion transport; regulation of calcium ion transmembrane transport via high voltage-gated calcium channel; cardiac conduction;
	来源：Amigo / QuickGO
直系同源
	786
	12299
	ENSG00000108878
	ENSMUSG00000020722
	Q06432
	O70578
	NM_000727
	NM_007582
	NP_000718
	NP_031608
	维基数据
檢視/編輯人類	檢視/編輯小鼠

电压依赖性钙通道γ1亚基是一种由CACNG1基因编码的蛋白质。^[5]^[6]

L型钙通道由五个亚基组成。由该基因编码的蛋白质代表γ亚基之一，是几种γ亚基蛋白质之一。这种特殊的γ亚基是骨骼肌1,4-二氢吡啶敏感性钙通道的一部分，是一种在激发 - 收缩偶联中起作用的完整膜蛋白。该基因是PMP-22 / EMP / MP20家族的神经元钙通道γ亚基基因亚家族的成员，并且位于具有两个相似的γ亚基编码基因的簇中。^[6]

参考文献

^ ^1.0 ^1.1 ^1.2 GRCh38: Ensembl release 89: ENSG00000108878 – Ensembl, May 2017
^ ^2.0 ^2.1 ^2.2 GRCm38: Ensembl release 89: ENSMUSG00000020722 – Ensembl, 2017年5月
^ Human PubMed Reference:. National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Mouse PubMed Reference:. National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Iles, D. E.; Segers, B.; Sengers, R. C.; Monsieurs, K.; Heytens, L.; Halsall, P. J.; Hopkins, P. M.; Ellis, F. R.; Hall-Curran, J. L. Genetic mapping of the beta 1- and gamma-subunits of the human skeletal muscle L-type voltage-dependent calcium channel on chromosome 17q and exclusion as candidate genes for malignant hyperthermia susceptibility. Human Molecular Genetics. 1993-7, 2 (7): 863–868 [2018-08-15]. ISSN 0964-6906. PMID 8395940. （原始内容存档于2018-08-15）. 请检查|date=中的日期值 (帮助)
^ ^6.0 ^6.1 CACNG1 calcium voltage-gated channel auxiliary subunit gamma 1 [Homo sapiens (human)] - Gene - NCBI. www.ncbi.nlm.nih.gov. [2018-08-15]. （原始内容存档于2019-02-15）.

[refGRCh38Ensembl-1] 1.0 ^1.1 ^1.2 GRCh38: Ensembl release 89: ENSG00000108878 – Ensembl, May 2017

[refGRCm38Ensembl-2] 2.0 ^2.1 ^2.2 GRCm38: Ensembl release 89: ENSMUSG00000020722 – Ensembl, 2017年5月

[3] Human PubMed Reference:. National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] Mouse PubMed Reference:. National Center for Biotechnology Information, U.S. National Library of Medicine.

[5] Iles, D. E.; Segers, B.; Sengers, R. C.; Monsieurs, K.; Heytens, L.; Halsall, P. J.; Hopkins, P. M.; Ellis, F. R.; Hall-Curran, J. L. Genetic mapping of the beta 1- and gamma-subunits of the human skeletal muscle L-type voltage-dependent calcium channel on chromosome 17q and exclusion as candidate genes for malignant hyperthermia susceptibility. Human Molecular Genetics. 1993-7, 2 (7): 863–868 [2018-08-15]. ISSN 0964-6906. PMID 8395940. （原始内容存档于2018-08-15）. 请检查|date=中的日期值 (帮助)

[:0-6] 6.0 ^6.1 CACNG1 calcium voltage-gated channel auxiliary subunit gamma 1 [Homo sapiens (human)] - Gene - NCBI. www.ncbi.nlm.nih.gov. [2018-08-15]. （原始内容存档于2019-02-15）.

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