ABT-202

ABT-202
识别信息
  • (R)-1-(Pyridin-3-yl)pyrrolidin-3-amine
CAS号309959-34-0  checkY[NIH]
PubChem CID
ChemSpider
UNII
化学信息
化学式C9H13N3
摩尔质量163.219
3D模型（JSmol）
  • N[C@@H]1CCN(C2=CC=CN=C2)C1
  • InChI=1S/C9H13N3/c10-8-3-5-12(7-8)9-2-1-4-11-6-9/h1-2,4,6,8H,3,5,7,10H2/t8-/m1/s1 ☒N
  • Key:LVGMMVAWLISWJD-MRVPVSSYSA-N ☒N

ABT-202是一种含氮有机化合物，分子式C9H13N3，由美國雅培公司开发，可作为菸鹼型乙醯膽鹼受體的激动剂，未经过臨床試驗。[1][2][3]

参考文献

  1. ^ Jain KK. Modulators of nicotinic acetylcholine receptors as analgesics. Current Opinion in Investigational Drugs. January 2004, 5 (1): 76–81. PMID 14983978. 
  2. ^ Romanelli MN, Gratteri P, Guandalini L, Martini E, Bonaccini C, Gualtieri F. Central nicotinic receptors: structure, function, ligands, and therapeutic potential. ChemMedChem. June 2007, 2 (6): 746–67. PMID 17295372. S2CID 34763474. doi:10.1002/cmdc.200600207. 
  3. ^ Xu N, Kim GE, Gregg H, Wagdy A, Swaine BA, Chang MS, El-Shourbagy TA. Automated 96-well liquid-liquid back extraction liquid chromatography-tandem mass spectrometry method for the determination of ABT-202 in human plasma. Journal of Pharmaceutical and Biomedical Analysis. September 2004, 36 (1): 189–95. PMID 15351065. doi:10.1016/j.jpba.2004.05.013. 
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