RH-34

RH-34
臨床資料
给药途径?
ATC碼
  • 未分配
法律規範狀態
法律規範
  • 巴: Class F2 (Prohibited psychotropics)[1]
  • Uncontrolled
识别信息
  • 3-[2-(2-methoxybenzylamino)ethyl]-1H-quinazoline-2,4-dione
CAS号1028307-48-3  checkY
PubChem CID
ChemSpider
UNII
CompTox Dashboard (EPA)
化学信息
化学式C18H19N3O3
摩尔质量325.37 g·mol−1
3D模型（JSmol）
  • O=C1C=2C(NC(=O)N1CCNCC3=C(OC)C=CC=C3)=CC=CC2
  • InChI=1S/C18H19N3O3/c1-24-16-9-5-2-6-13(16)12-19-10-11-21-17(22)14-7-3-4-8-15(14)20-18(21)23/h2-9,19H,10-12H2,1H3,(H,20,23) ☒N
  • Key:NUAJBITWGGTZCM-UHFFFAOYSA-N ☒N

RH-34是一种含氮有机化合物，分子式C
18H
19N
3O
3，是5-HT2A受体的选择性部分激动剂。[2][3][4]

它可以2-氨基苯甲酸甲酯和氯甲酸乙酯为原料，经多步反应制得。[2]

参考文献

  1. ^ Anvisa. RDC Nº 804 - Listas de Substâncias Entorpecentes, Psicotrópicas, Precursoras e Outras sob Controle Especial [Collegiate Board Resolution No. 804 - Lists of Narcotic, Psychotropic, Precursor, and Other Substances under Special Control]. Diário Oficial da União. 2023-07-24 (2023-07-25) [2023-08-27]. （原始内容存档于2023-08-27） （巴西葡萄牙语）. 
  2. ^ 2.0 2.1 Ralf Heim. Synthese und Pharmakologie potenter 5-HT2A-Rezeptoragonisten mit N-2-Methoxybenzyl-Partialstruktur. Entwicklung eines neuen Struktur-Wirkungskonzepts. (German)
  3. ^ Maria Silva. Theoretical study of the interaction of agonists with the 5-HT2A receptor. Universität Regensburg, 2009.
  4. ^ Silva ME, Heim R, Strasser A, Elz S, Dove S. Theoretical studies on the interaction of partial agonists with the 5-HT(2A) receptor. Journal of Computer-aided Molecular Design. January 2011, 25 (1): 51–66. Bibcode:2011JCAMD..25...51S. CiteSeerX 10.1.1.688.2670 可免费查阅. PMID 21088982. S2CID 3103050. doi:10.1007/s10822-010-9400-2. 
This article is issued from Wikipedia. The text is available under Creative Commons Attribution-Share Alike 4.0 unless otherwise noted. Additional terms may apply for the media files.