C5a受体

C5a受体
标识符
代号C5AR1
扩展标识OMIM113995MGI88232;HomoloGene:20413GeneCardsC5AR1;OMA:C5AR1 - orthologs
直系同源
物種人類小鼠
Entrez
728
12273
Ensembl
ENSG00000197405
ENSMUSG00000049130
UniProt
P21730
P30993
mRNA序列
NM_001736
NM_001173550
​NM_007577
蛋白序列
NP_001727
NP_001167021
​NP_031603
基因位置Chr 19:47.29 – 47.32 MbChr 7:15.98 – 15.99 Mb
PubMed查询[3][4]
维基数据
檢視/編輯人類檢視/編輯小鼠

C5a受体(英語:C5a receptor或称补体成分5a受体1,complement component 5a receptor 1C5AR1CD88Cluster of Differentiation 88)是一种与补体C5a相结合的G蛋白偶联受体[5]

C5a受体结构及其与配体结合信号转导相关的氨基酸残基

细胞

C5a受体表达于以下细胞:[6]

另见

  • 补体成分5a

参考文献

  1. ^ 1.0 1.1 1.2 GRCh38: Ensembl release 89: ENSG00000197405 – Ensembl, May 2017
  2. ^ 2.0 2.1 2.2 GRCm38: Ensembl release 89: ENSMUSG00000049130Ensembl, 2017年5月
  3. ^ Human PubMed Reference:. National Center for Biotechnology Information, U.S. National Library of Medicine. 
  4. ^ Mouse PubMed Reference:. National Center for Biotechnology Information, U.S. National Library of Medicine. 
  5. ^ Gerard C, Gerard NP. C5A anaphylatoxin and its seven transmembrane-segment receptor. Annu. Rev. Immunol. 1994, 12: 775–808. PMID 8011297. doi:10.1146/annurev.iy.12.040194.004015. 
  6. ^ Klos A, Wende E, Wareham KJ, Monk PN. International Union of Pharmacology. LXXXVII. Complement peptide C5a, C4a, and C3a receptors. Pharmacol. Rev. 2013, 65 (1): 500–43. PMID 23383423. doi:10.1124/pr.111.005223. 

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